The Coxsackie B viruses are members of the enterovirus (link) genus and are the most common agent for myocarditis and dilated cardiomyopathy constituting 50% of infections. Myocarditis is an uncommon disease that occurs in only 1% of the American population. Myocarditis predominantly affects middle-aged men with the average age of disease onset occurring around 42 years of age. The incubation period for most coxsackie virus infections is about two to ten days and onset of cardiac symptoms typically occurs two weeks after viral infection. The coxsackie B viruses, like most enteroviruses are transmitted fecal-orally and through direct contact with mucosal secretions.